Elements And Macromolecules In Organisms Pdf

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Identify the initial reactants, final products, and general purposes of photosynthesis and cellular respiration. Describe the relationship between photosynthesis and cellular respiration in photosynthetic organisms. Compare and contrast the functions and structures of proteins, lipids, carbohydrates, and nucleic acids.

CH103 – Chapter 8: The Major Macromolecules

A macromolecule is a very large molecule , such as a protein. They are composed of thousands of covalently bonded atoms. Many macromolecules are the polymerization of smaller molecules called monomers. The most common macromolecules in biochemistry are biopolymers nucleic acids , proteins, and carbohydrates and large non-polymeric molecules such as lipids and macrocycles. A molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

In many cases, especially for synthetic polymers, a molecule can be regarded as having a high relative molecular mass if the addition or removal of one or a few of the units has a negligible effect on the molecular properties. This statement fails in the case of certain macromolecules for which the properties may be critically dependent on fine details of the molecular structure. Usage of the term to describe large molecules varies among the disciplines.

For example, while biology refers to macromolecules as the four large molecules comprising living things, in chemistry , the term may refer to aggregates of two or more molecules held together by intermolecular forces rather than covalent bonds but which do not readily dissociate.

According to the standard IUPAC definition, the term macromolecule as used in polymer science refers only to a single molecule. For example, a single polymeric molecule is appropriately described as a "macromolecule" or "polymer molecule" rather than a "polymer," which suggests a substance composed of macromolecules.

Because of their size, macromolecules are not conveniently described in terms of stoichiometry alone. The structure of simple macromolecules, such as homopolymers, may be described in terms of the individual monomer subunit and total molecular mass. Complicated biomacromolecules, on the other hand, require multi-faceted structural description such as the hierarchy of structures used to describe proteins.

In British English , the word "macromolecule" tends to be called " high polymer ". Another common macromolecular property that does not characterize smaller molecules is their relative insolubility in water and similar solvents , instead forming colloids. Many require salts or particular ions to dissolve in water. Similarly, many proteins will denature if the solute concentration of their solution is too high or too low. High concentrations of macromolecules in a solution can alter the rates and equilibrium constants of the reactions of other macromolecules, through an effect known as macromolecular crowding.

All living organisms are dependent on three essential biopolymers for their biological functions: DNA , RNA and proteins. In general, they are all unbranched polymers, and so can be represented in the form of a string. Indeed, they can be viewed as a string of beads, with each bead representing a single nucleotide or amino acid monomer linked together through covalent chemical bonds into a very long chain.

In most cases, the monomers within the chain have a strong propensity to interact with other amino acids or nucleotides.

Because of the double-stranded nature of DNA, essentially all of the nucleotides take the form of Watson-Crick base pairs between nucleotides on the two complementary strands of the double-helix. In contrast, both RNA and proteins are normally single-stranded.

Therefore, they are not constrained by the regular geometry of the DNA double helix, and so fold into complex three-dimensional shapes dependent on their sequence. These different shapes are responsible for many of the common properties of RNA and proteins, including the formation of specific binding pockets , and the ability to catalyse biochemical reactions. DNA is an information storage macromolecule that encodes the complete set of instructions the genome that are required to assemble, maintain, and reproduce every living organism.

DNA and RNA are both capable of encoding genetic information, because there are biochemical mechanisms which read the information coded within a DNA or RNA sequence and use it to generate a specified protein. On the other hand, the sequence information of a protein molecule is not used by cells to functionally encode genetic information.

DNA has three primary attributes that allow it to be far better than RNA at encoding genetic information. First, it is normally double-stranded, so that there are a minimum of two copies of the information encoding each gene in every cell.

Second, DNA has a much greater stability against breakdown than does RNA, an attribute primarily associated with the absence of the 2'-hydroxyl group within every nucleotide of DNA. Third, highly sophisticated DNA surveillance and repair systems are present which monitor damage to the DNA and repair the sequence when necessary.

Analogous systems have not evolved for repairing damaged RNA molecules. Consequently, chromosomes can contain many billions of atoms, arranged in a specific chemical structure. Proteins are functional macromolecules responsible for catalysing the biochemical reactions that sustain life.

The single-stranded nature of protein molecules, together with their composition of 20 or more different amino acid building blocks, allows them to fold in to a vast number of different three-dimensional shapes, while providing binding pockets through which they can specifically interact with all manner of molecules.

In addition, the chemical diversity of the different amino acids, together with different chemical environments afforded by local 3D structure, enables many proteins to act as enzymes , catalyzing a wide range of specific biochemical transformations within cells.

In addition, proteins have evolved the ability to bind a wide range of cofactors and coenzymes , smaller molecules that can endow the protein with specific activities beyond those associated with the polypeptide chain alone. RNA encodes genetic information that can be translated into the amino acid sequence of proteins, as evidenced by the messenger RNA molecules present within every cell, and the RNA genomes of a large number of viruses.

The single-stranded nature of RNA, together with tendency for rapid breakdown and a lack of repair systems means that RNA is not so well suited for the long-term storage of genetic information as is DNA. In addition, RNA is a single-stranded polymer that can, like proteins, fold into a very large number of three-dimensional structures.

Some of these structures provide binding sites for other molecules and chemically-active centers that can catalyze specific chemical reactions on those bound molecules. Carbohydrate macromolecules polysaccharides are formed from polymers of monosaccharides.

Polysaccharides perform numerous roles in living organisms, acting as energy stores e. Many carbohydrates contain modified monosaccharide units that have had functional groups replaced or removed. Polyphenols consist of a branched structure of multiple phenolic subunits. They can perform structural roles e. Some examples of macromolecules are synthetic polymers plastics , synthetic fibers , and synthetic rubber , graphene , and carbon nanotubes.

Polymers may be prepared from inorganic matter as well as for instance in inorganic polymers and geopolymers. From Wikipedia, the free encyclopedia. A macromolecule is a large molecule that is composed of atoms. For the journal, see Macromolecules journal.

For the journal formerly known as Macromolecular Chemistry, see Macromolecular Chemistry and Physics. IUPAC definition. Macromolecule Large molecule A molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Notes 1. If a part or the whole of the molecule fits into this definition, it may be described as either macromolecular or polymeric , or by polymer used adjectivally.

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W Pure and Applied Chemistry. Helvetica Chimica Acta. Journal of Chemical Education. Bibcode : JChEd.. Cell Sci. Biochemistry, 7th ed. Biochemistry Berg.

Molecular Biology of the Cell 5th edition, Extended version. New York: Garland Science. The Cartoon Guide to Genetics. Collins Reference. The Manga Guide to Molecular Biology. No Starch Press. Bauer; Volker Enkelmann; Uwe M. Wiesler; Alexander J. Chemistry: A European Journal. Hierarchy of life.

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Download as PDF Printable version. Wikimedia Commons. Lipids are any organic nonpolar molecule. Some lipids are held together by ester bonds; some are huge aggregates of small molecules held together by hydrophobic interactions.

Structure and function

A macromolecule is a very large molecule , such as a protein. They are composed of thousands of covalently bonded atoms. Many macromolecules are the polymerization of smaller molecules called monomers. The most common macromolecules in biochemistry are biopolymers nucleic acids , proteins, and carbohydrates and large non-polymeric molecules such as lipids and macrocycles. A molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.

Nutrients are the molecules that living organisms require for survival and growth but that animals and plants cannot synthesize themselves. Animals obtain nutrients by consuming food, while plants pull nutrients from soil. Many critical nutrients are biological macromolecules. Staudinger was the first to propose that many large biological molecules are built by covalently linking smaller biological molecules together. Biological macromolecules play a critical role in cell structure and function.


Name: MACROMOLECULES. Date: I. ELEMENTS AND MACROMOLECULES IN ORGANISMS: Most common elements in living things are carbon, hydrogen.


Monomers and Polymers

Phytochemical Methods pp Cite as. The macromolecules of plants are distinguished from all other constituents by their high molecular weight. This may vary from 10, to over 1,,, whereas in other plant metabolites the molecular weight is rarely above 1, Chemical characterization in the first instance therefore depends on identifying these smaller units.

Elements & Macromolecules in Organisms

Nucleotides polymerize to yield nucleic acids.

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Cells are made of many complex molecules called macromolecules, such as proteins, nucleic acids RNA and DNA , carbohydrates, and lipids. The macromolecules are a subset of organic molecules any carbon-containing liquid, solid, or gas that are especially important for life. The fundamental component for all of these macromolecules is carbon. Individual carbon atoms have an incomplete outermost electron shell. With an atomic number of 6 six electrons and six protons , the first two electrons fill the inner shell, leaving four in the second shell. Therefore, carbon atoms can form up to four covalent bonds with other atoms to satisfy the octet rule.

NCBI Bookshelf. Cooper GM. The Cell: A Molecular Approach. Sunderland MA : Sinauer Associates; Cells are composed of water, inorganic ions, and carbon-containing organic molecules.

3: Biological Macromolecules

Students should be able to explain and apply core concepts of macromolecular structure and function, including the nature of biological macromolecules, their interaction with water, the relationship between structure and function, and frequently encountered mechanisms for regulating their function.

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3 Comments

  1. Hedvige B. 09.04.2021 at 20:41

    All compounds can be classified in two broad categories - -- organic and inorganic compounds.

  2. Aubert R. 12.04.2021 at 02:03

    There are four classes of macromolecules (polysaccharides or carbohydrates, triglycerides or lipids, polypeptides or proteins, and nucleic acids such as DNA &​.

  3. RayГ©n G. 14.04.2021 at 03:36

    NCBI Bookshelf.